Assad, who has tried in vain to crush the 5-month-old revolt, appears increasingly out of touch as he refuses to acknowledge the hundreds of thousands of people demanding his ouster, analysts say. Instead, he blames the unrest on Islamic extremists and thugs.

But many observers say Assad should heed the lessons of Libya.

"Gadhafi is gone; now it's your turn, Bashar!" protesters shouted in several cities across the country hours after Assad dismissed calls to step down during an interview on state TV. Security forces opened fire in the central city of Homs, killing at least one person.

"Leaders should know that they will be able to remain in power as long as they remain sensitive to the demands of the people," Turkish Foreign Minister Ahmet Davutoglu said in Addis Ababa, Ethiopia, according to Turkey's Anatolia news agency.

Turkey, a former close ally of Syria and an important trade partner, has grown increasingly frustrated with Damascus over its deadly crackdown. The violence has left Syria facing the most serious international isolation in decades, with widespread calls for Assad to step down.

Human rights groups say more than 2,000 people – most of them unarmed protesters – have been killed in the government's crackdown on the uprising. Continued...